Neuro-Electronics Research Flanders

NERF Seminar: Cellular dissection of head-centred visual processing in V1 Layer 6

Speaker: Troy Margrie
Affiliation: Professor of Systems Neuroscience, The Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, UK
Time: Thursday, September 06, 2018, 11:00 am
Location: Imec Tower room 2.A
Host: Karolina Socha

Of all the cortical layers, least is known about the function of Layer 6, except that it contains two principal cell types, cortico-cortical (CC) and cortico-thalamic (CT) neurons. We have applied a barrage of tools including in vivo electrical recording, viral tracing and circuit mapping, behavioural and theoretical approaches to dissect the potential role of these two cell types. These data indicated a distinct role for CC and CT cells in visual processing and unveiled a completely novel circuit for integration of “self-motion” signals arising from the motion of the head. We speculate that visual output from Layer 6 is egocentric and contextually dependent on the motion status of the animal.